Antidiabetic Properties Of Oxovanadium (Iv) Ion Complexes: Analysis And Prospects
Keywords:
Oxovanadium (IV), metal complexes, antidiabetic activity, insulin signalingAbstract
This article provides an analytical overview of the antidiabetic properties of oxovanadium (IV) complexes, focusing on their structural characteristics, molecular mechanisms of action, and pharmacological prospects. The influence of ligand nature and coordination environment on the biological activity of VO²⁺ complexes is examined, along with their ability to modulate insulin signaling pathways, suppress gluconeogenesis, and reduce oxidative stress. Available studies indicate the significant therapeutic potential of these compounds in disorders of carbohydrate metabolism. Evaluation of pharmacokinetic and toxicological parameters highlights the necessity of designing new, selective, and safe oxovanadium-based therapeutic formulations for potential clinical use.
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